ADARx Pharmaceuticals

ADARx Pharmaceuticals, Inc. is a late-clinical stage biotechnology company focused on developing next-generation siRNA therapeutics designed to treat a broad spectrum of diseases. The Company is focused on advancing and expanding its pipeline of highly potent, selective and durable siRNA therapeutic candidates, including three clinical-stage programs and two advanced preclinical programs. siRNA, or small interfering RNA, therapeutics represent a significant advancement in precision medicine by addressing diseases at the genetic level (mRNA or RNA) while avoiding permanent alterations to a patient’s genome (DNA). Its hepatic-targeted programs include Agazisiran, Onvuzosiran, and ADX-626. Its extrahepatic-targeted programs include ADX-077 and ADX-199. ADX-077 is designed to reduce body weight and fat while preserving lean mass. ADX-626, is in development for secondary stroke prevention with additional clinical potential for stroke prevention in atrial fibrillation.